This one gets me every time. Your watching your Twitter stream, maybe on the web or through Tweetdeck or some other tool, and all of a sudden you get bombarded with 10 or more tweets from a corporate account, newspaper or other organization. I’ve seen affiliates blast 15 in the space of 10 seconds and one of our local Idaho newspapers launch 5 or more.
By doing this you are very likely reducing the chance that those tweets will actually be read. if there is a potential action solicited from your tweet, your followers are less likely to take that action. You may also be annoying your followers, have you noticed many un-following you? Many Twitterers use other tools to follow their friends and you, and often it only displays a few at a time, so many of your posts are most likely not even seen.
There are man Twitter plugins, if you are using a blog, that allows you to automatically update your Twitter account as posts are posted. These may help you to update your account on the fly and without your intervention.
I’ve used both and they work great. I highly recommend if you can’t use those tools to update your account as new information becomes available. Users are more likely to ready what you have to say when there is one at a time.